Microarray technology encompasses a few relatively well-established methods and numerous applications that are in various stages of development. Apart from their use as a tool for diagnostic testing ...

Completion of the Human Genome Project has been rapidly followed by the emergence of high-throughput technologies that combine automation, miniaturization, and many other strategies and tools to ...

Yes, many are attracted to next-generation sequencing, but loyalty to chip-based phenotyping has its rewards, particularly in screens of large sample sets. The microarray, the legacy technology for ...

A survey of scientists developing bioprocesses found efficiency to be the top concern, with pressure growing each year to “produce more, do it more quickly, and do so with fewer resources.” 1 Yet, ...

Microarrays provide a way of organizing biological samples for high-throughput analysis. Samples are arranged in columns and rows upon a support surface consisting of a glass slide, a nitrocellulose ...

A recent study highlights how DNA microarray technology enables high-throughput gene analysis, supporting variation detection, expression profiling, and clinical research. By refining probe design and ...

A protein microarray consists of the immobilization of proteins in organized rows and columns upon a support structure. The structure of the protein microarray allows for high-throughput analysis of ...

The human genome project was undertaken to determine the human DNA sequence and analyze variation among individuals. To make use of this information, tools were developed that could collect and ...

In each type of cell, like a muscle cell or a skin cell, different genes are expressed (turned on) or silenced (turned off). If the cells that are turned on mutate, they could—depending on what role ...

The research community's rapid acceptance of microarrays notwithstanding, technical challenges remain. Biochip developers continue to grapple with these issues while upgrading their offerings and ...

Tissue microarrays combines tens to hundreds of paraffin-embedded tissue cores into a single paraffin block. It is a practical and highly effective technique for high-throughput analyses of various ...

Response to Neoadjuvant Chemotherapy Combined With Regional Hyperthermia Predicts Long-Term Survival for Adult Patients With Retroperitoneal and Visceral High-Risk Soft Tissue Sarcomas ABSTRACT: ...