The TGF-β signalling pathway is crucial in the regulation of various cellular processes during development in multicellular organisms 1. TGF-β is a homodimeric cytokine and has three homologous ...
Optogenetic systems enable precise spatial and temporal control of cell behavior. We engineered a light-activated CRISPR-Cas9 effector (LACE) system that induces transcription of endogenous genes in ...
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