DNA coding theory bridges the disciplines of mathematics, computer science and molecular biology by applying advanced algebraic and combinatorial techniques to the design of nucleotide sequences. This ...

Decades of research has viewed DNA as a sequence-based instruction manual; yet every cell in the body shares the same genes – so where is the language that writes the memory of cell identities?

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

The non-coding genome, once dismissed as "junk DNA", is now recognized as a fundamental regulator of gene expression and a key player in understanding complex diseases. Following the landmark ...

Researchers discover a unique genetic code in Antarctic archaea that encodes a rare amino acid, potentially advancing protein ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

Stay up to date on the latest science with Brush Up Summaries. Article reviewed by Ninning Liu, PhD from the Wyss Institute at Harvard University. Similar to retail stores that use standardized ...

Repeats of DNA sequences, often referred to as 'junk DNA' or 'dark matter,' that are found in chromosomes and could contribute to cancer or other diseases have been challenging to identify and ...

Genetic features known as transposons make up a large portion of many mammalian genomes, including humans', and they are now known to play a variety of roles. Some transposable elements (TEs) could be ...

Structural variations (SVs)—large-scale changes in DNA sequence—play a crucial role in shaping traits such as yield, quality, and environmental adaptation in crops.